Description

INTRODUCTION

F-Phenibut HCl (also known as 4-Fluorophenibut, Fluorophenibut, Fluorobut and CGP-11130) is a several-fold more potent derivative of Phenibut. F-Phenibut (Fluorophenibut) has a behavioural potency of approximately five to tenfold higher than Phenibut in vivo, with approximately sixfold higher affinity as a GABA_B agonist than Phenibut.

F-Phenibut  is a central nervous system depressant and closely related structural analog of Phenibut. F-Phenibut possesses an effect profile similar to Phenibut but with a faster onset, significantly increased potency, and shorter duration.

Other nootropics take a while to kick in while 4 Fluorophenyl takes only 20 minutes to take effect. For others, it takes up to 60 minutes before they feel any difference.

The effect can last between 6 to 8 hours.

BENEFITS AND EFFECTS

Anxiety-reduction is the most commonly recognized benefit of Phenibut and was documented by Izyaslav Lapin. Anxiety may be caused by the brain focusing on and overworking unimportant details. Turning off this distracting neuron processing may free the person to process a broader, more productive range of stimuli.

Reduces Social Anxiety

This anxiolytic effect can lead to more rewarding social interactions. There is some limited research supporting enhanced cognitive processing following Phenibut consumption, but the primary and supported benefit is anxiolytic.

Restores Healthy Sleep Patterns

People living through depression, anxiety, stressful life events, and hormonal changes, like menopause, often report deteriorating sleep quality. Some have been unsuccessful using Melatonin and are unwilling to use pharmaceutical sleep aids. The lack of quality sleep can create an unbroken cycle of impaired cognitive processing, leading to more anxiety, and resulting in even more lost sleep. Phenibut used as an ataractic supplement or sedative can restore helpful, natural sleep patterns, duration, and quality.

‘HOW IT WORKS

Gamma-aminobutyric acid (GABA) is a naturally occurring brain inhibitory neurotransmitter. The blood-brain barrier makes taking supplements of GABA ineffective, but Phenibut can cross the barrier because it has an additional Phenyl group molecule or ring. Once in the brain, it slows down the neuronal process. GABA opens up channels in the neurons, decreases the function of other neurotransmitters, and reduces collective anxiety in the neuron. It is not exactly clear if Phenibut binds to the GABA receptor or not. Studies have shown that it does and others that it might but only in high concentrations. Lapin’s study also found that Phenibut increases levels of the body’s dopamine. Dopamine is a well-known, often-studied neurotransmitter in the central nervous system that has been shown to regulate emotion and promote motivation and happiness. It is believed that dopamine depletion leads to Parkinson’s disease.

RESEARCH DOSAGE

F-Phenibut is a powerful compound that is best started at a low dosage with careful monitoring. While the exact ideal Phenibut dosage is not known and can vary from person to person, some users report that 100mg of F-Phenibut is approximately equal to about 2 grams of common Phenibut. Many users report that doses between 50 mg and 250 mg daily helps them to operate at their optimal level. Others have needed slowly to increase ingestion, gradually reaching levels closer to the 400 mg daily target. F-Phenibut lasts up to 8 hours in the human body, so once a dose is ingested, keep a 4-hour window before taking another dose and cycle it up every 2 weeks of daily intake.

SIDE EFFECTS

Whenever a new food, supplement, or medication is introduced, the best source of criticism is the human body itself. Any person deciding to take Phenibut should start with a low dose and be tuned into the feedback provided by his or her body.

In addition to the “drunkenness” feeling that overdosing can produce, other side effects may include light-headedness and dizziness. Other users have reported fatigue, nausea, and stomach discomfort following ingestion of Phenibut. Furthermore, individuals on epilepsy medication or MAO inhibitors should consult with their doctor before taking Phenibut.

Alcohol and other sedatives should be avoided when taking F-Phenibut due to synergistic effects.

F-Phenibut should not be supplemented daily. It has the potential to be addictive, especially when taken excessively. If taken regularly, tolerance will also be developed reducing its efficacy. Limiting usage, as others have, to a couple of times each week will minimize the possibility of addiction and tolerance.

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